Calcium and Vitamin D3 Bone Support Tablets

Calcium and Vitamin D3 Bone Support Tablets

Finished tablet · calcium carbonate or citrate with cholecalciferol (D3)

Finished-dose tablets pairing calcium carbonate or calcium citrate with cholecalciferol (vitamin D3), built to the buyer's strength, coating and label. Bulk, blister and private-label runs.

Specifications

Product typeFinished-dose food supplement tablet made to the buyer's formula, artwork and market; not supplied as a bulk chemical.
Calcium sourcesCalcium carbonate (CAS 471-34-1), ~40% elemental Ca; calcium citrate, Ca3(C6H5O7)2 (CAS 813-94-5), ~21% elemental Ca. Blends or tricalcium phosphate to order.
Vitamin D3Cholecalciferol, CAS 67-97-0, C27H44O, MW 384.64. USP/Ph.Eur. potency basis: 1 IU = 0.025 mcg, so 1 mcg = 40 IU.
Typical strengths500 or 600 mg elemental calcium with 400 to 1000 IU (10 to 25 mcg) vitamin D3 per tablet; other ratios and once-daily formats to order.
Vitamin D3 raw formCold-water-dispersible beadlet at 100,000 IU/g or 40,000 IU/g on acacia and modified starch, with a declared overage to hold label claim through shelf life.
AppearanceWhite to off-white round or oblong film-coated tablet; buyer-specified size, debossing and coating colour.
Assay and label claimCalcium by complexometric titration or ICP-OES; vitamin D3 by HPLC. Release limits set with overage so that claim is met to end of shelf life.
Physical testsDisintegration not more than 30 minutes in purified water; friability not more than 1.0%; hardness and weight variation to the agreed in-house spec.
Heavy metalsLead, arsenic, cadmium and mercury controlled on the finished tablet against USP <2232> and FSSAI limits; tighter buyer limits accepted on request.
MicrobiologyTotal plate count, yeast and mould within supplement limits; E. coli, Salmonella and S. aureus absent. Full result set on each batch COA.
Origin and diet statusLanolin-sourced D3 is ovine in origin: vegetarian but not vegan. Lichen-derived D3 or yeast-derived D2 available where a vegan claim is required.
Allergen statusFree from milk, egg, soy, fish, crustacean, gluten, peanut and tree nut on the standard excipient set; soy is declared if a soy tocopherol carrier is used.
Gelatin cautionSome D3 beadlets are gelatin-based (fish or bovine). Specify an acacia/starch beadlet where fish allergen or bovine origin must be excluded.
Shelf life24 months from manufacture at 25 C or below and 60% RH or below in the sealed pack.
HS code2106 90 99
This is a finished dosage product rather than a bulk raw material: Thovek supplies the pressed, coated and packed tablet made to the buyer's own strength, shape and artwork. The calcium side is normally calcium carbonate (CAS 471-34-1), which carries roughly 40% elemental calcium and therefore gives the smallest tablet for a given claim, or calcium citrate, Ca3(C6H5O7)2 (CAS 813-94-5), at roughly 21% elemental calcium, which needs a larger tablet but is the usual choice where a buyer wants a salt that is not dependent on gastric acid for dissolution. Blends of the two, and tricalcium phosphate as a third source, are all available. The vitamin side is cholecalciferol (CAS 67-97-0, C27H44O, MW 384.64), dosed against the USP and Ph.Eur. potency basis in which one International Unit equals 0.025 micrograms, so one microgram equals 40 IU. Common builds run 500 to 600 mg elemental calcium with 400 to 1000 IU (10 to 25 mcg) of D3 per tablet. Cholecalciferol is a fragile molecule inside a mineral-rich tablet, so it is added as a cold-water-dispersible beadlet, typically 100,000 IU/g on an acacia and modified-starch matrix, with a declared overage so that the HPLC assay still meets label claim at the end of shelf life. Two declarations matter commercially. First, origin: the standard commercial cholecalciferol is made from lanolin, the wax from sheep wool, which makes it vegetarian but not vegan; lichen-derived D3 or yeast-derived D2 is available where the buyer needs a vegan claim. Second, allergens: some D3 beadlets are built on fish or bovine gelatin rather than acacia, so if the finished pack must carry a fish-free or non-bovine declaration, the beadlet type has to be written into the specification and not left to the encapsulator's default. Every batch ships with a certificate of analysis covering calcium by titration or ICP-OES, vitamin D3 by HPLC, disintegration, friability, heavy metals and full microbiology, together with allergen and origin statements, a nutrition panel and a stability summary. Formats include HDPE jars, Alu-Alu blisters and bulk tablets for the buyer's own packing line. Thovek describes composition and established nutrient function only. Calcium and vitamin D are recognised nutrients with defined reference intakes in India (ICMR-NIN), the EU and the US, and any market-specific claim wording, dose cap or warning statement remains the buyer's responsibility to substantiate and register.

Applications

Women's bone health tabletsPost-menopausal daily supplementsPrenatal and postnatal rangesPharmacy private-label linesCalcium magnesium zinc combinationsChewable and effervescent variantsInstitutional and tender supplyContract manufacturing tablet runs

Available grades

Food and nutraceutical grade, produced under FSSAI licence to the Health Supplements and Nutraceuticals Regulations 2016; actives to IP, USP or Ph.Eur. monographs. Vegetarian as standard (lanolin D3) or vegan (lichen D3 or yeast D2). Sugar-free, lactose-free and gluten-free builds available. Halal and kosher certification, GMP and HACCP documentation on request. Film-coated, chewable and effervescent variants.

Packaging: HDPE jars of 30, 60, 90 or 120 tablets with induction seal and silica-gel desiccant; Alu-PVdC or Alu-Alu blisters of 10 to 15 tablets per strip in printed cartons; bulk tablets in double food-grade LDPE liners inside 20 to 25 kg HDPE drums with desiccant for buyers who pack in-market. Shipper cartons palletised and stretch-wrapped, with batch, manufacture and expiry marking to the buyer's artwork.

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