Finished capsules combining 95% curcuminoid turmeric extract with 95% piperine black pepper extract, assayed by HPLC on the filled capsule rather than on component certificates. Vegan HPMC shell.
| Product format and composition | Finished two-piece hard capsule. Standard 500 mg fill: Curcuma longa L. rhizome extract 495 mg with Piper nigrum L. fruit extract 5 mg, a 99:1 build. Other ratios to order |
| Curcuminoid component | Turmeric extract NLT 95.0% total curcuminoids by HPLC, giving about 470 mg curcuminoids per 500 mg capsule. Lower-assay 10:1 and 20:1 extracts where a lighter load is wanted |
| Curcuminoid identity | Curcumin CAS 458-37-7, C21H20O6, MW 368.38, melting point about 183 C, 75 to 80% of the fraction; demethoxycurcumin 15 to 20%; bisdemethoxycurcumin 3 to 5% |
| Piperine component | Black pepper extract NLT 95.0% piperine by HPLC, 5 mg per capsule giving about 4.75 mg piperine. Piperine CAS 94-62-2, C17H19NO3, MW 285.34, melting point 131 to 135 C |
| Finished-capsule assay | Curcuminoids and piperine assayed on the filled capsule by HPLC, not carried over from component certificates. Content uniformity issued per lot; piperine is the low-dose marker |
| Appearance and solubility | Free-flowing orange-yellow to yellow-brown fill, characteristic aromatic odour. Practically insoluble in water; soluble in ethanol, acetone and glacial acetic acid |
| Capsule shell | HPMC (hypromellose) size 0 or 00 as standard, vegan and titanium-dioxide-free. Bovine gelatin only on written instruction; porcine gelatin never used unless specified |
| Fill weight, uniformity, disintegration | Ph. Eur. 2.9.5 at 300 mg or more average mass: individual capsules within 7.5%. Disintegration NMT 30 minutes, Ph. Eur. 2.9.1 / USP <701>, medium stated on the protocol |
| Adulterant screening | Every lot negative for metanil yellow, Sudan dyes and lead chromate. Synthetic curcumin excluded; natural origin by carbon-14 biobased content, ASTM D6866, on request |
| Mycotoxins | EU Regulation 2023/915 for turmeric and fruits of Piper spp.: aflatoxin B1 NMT 5.0 ug/kg and total aflatoxins NMT 10.0 ug/kg, applied to the fill and verified per lot |
| Allergen and diet status | Vegan and vegetarian with the HPMC shell, wholly plant-derived and non-GMO. Free of milk, egg, soy, fish, crustacean, peanut, tree nut, sesame, mustard, celery and gluten |
| Contaminants and microbiology | Lead NMT 3.0, arsenic NMT 1.0, cadmium NMT 1.0, mercury NMT 0.1 ppm; residual solvents within ICH Q3C Class 3. TPC NMT 10,000 cfu/g, yeast and mould NMT 500 cfu/g, pathogens absent |
| Shelf life and storage | 24 months in the sealed original pack. Curcumin is light- and alkali-sensitive: opaque HDPE bottle with desiccant or alu-alu blister, stored below 25 C away from light |
| HS code | 21069099 (India ITC-HS) as a finished capsule food supplement. The unencapsulated bulk blend is a different article. Importing customs authority decides |
Fill weights 300, 400, 500 and 600 mg; ratios 100:1, 99:1, 50:1 and 20:1 curcuminoid extract to piperine extract, or any split to contract. Alternative builds: whole turmeric rhizome powder carried with extract, 10:1 and 20:1 native extracts, water-dispersible and self-emulsifying curcumin, curcumin phospholipid complex, and versions extended with ginger, tulsi or boswellia, each quoted on its own specification. Shells in HPMC, pullulan or bovine gelatin, sizes 0, 00 and 1, clear, coloured or printed. Organic (NOP/EU), kosher and halal certified lots. Bottled, blistered or bulk unlabelled.
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