Neem extract (Azadirachta indica)

Neem here is the leaf of Azadirachta indica A. Juss., a Meliaceae tree grown across the Indian plains and carried in older literature under the synonym Melia azadirachta L. Thovek supplies a leaf extract standardised on total bitters, typically at 5% or 10% by gravimetry, with native ratio grades from 4:1 to 10:1 where the buyer wants an unadjusted profile. The bitter fraction is a limonoid mixture led by nimbin, salannin and nimbolide, supported by flavonoids and phenolics, and the whole profile is fixed by HPTLC fingerprint rather than by a single marker compound. The commercially decisive question on neem is which part of the tree the material came from. Azadirachtin, the compound most buyers associate with the name, sits almost entirely in the seed kernel — reported at roughly 200 to 900 ppm in kernel extracts against only about 10 to 100 ppm in leaf — so any specification calling for azadirachtin at percentage level describes a seed product and not this one. Seed-derived azadirachtin concentrates are, in most jurisdictions, regulated as plant-protection actives rather than food ingredients and classify in heading 3808 rather than chapter 13, which changes both the registration burden and the duty position. Thovek keeps the leaf and seed supply chains separate and states the plant part on the certificate of analysis for every lot. The extract is Indian origin and wholly plant-derived, vegan and vegetarian suitable, non-GMO, and free of milk, egg, soy, fish, crustacean, cereal gluten, peanut and tree-nut source material — the neem fruit is a drupe and is not a tree nut for allergen-labelling purposes. Market access varies more for neem than for most Ayurvedic botanicals: it is not a self-evident pre-1997 European food, and buyers placing neem food supplements on the EU market should confirm novel-food status with their competent authority before shipment. Thovek describes composition and botanical identity only and makes no health, nutrition or disease claim; setting label warnings, including any restriction on use during pregnancy, is the buyer's responsibility in their own market.