Gymnema sylvestre extract

Gymnema sylvestre R.Br. is a woody climber of the Apocynaceae, native to India and long used in Ayurveda under the names Madhunashini and Gurmar, both of which translate as sugar destroyer. Thovek supplies the leaf extract: dried, milled leaf extracted with water and/or food-grade ethanol, concentrated and spray dried to a free-flowing green to green-brown powder. The characteristic constituents are the gymnemic acids, a family of triterpenoid saponins that share the aglycone gymnemagenin (C30H50O6, MW 506.7), alongside the peptide gurmarin, related gymnemasaponins and leaf flavonols. The single most important commercial point on this ingredient is the assay method. Gymnemic acids are quantified either gravimetrically or chromatographically after hydrolysis to gymnemagenin, and the two do not give comparable numbers: published method comparisons consistently show gravimetry returning markedly higher figures than HPLC. A 75% gymnemic acids extract is almost always a gravimetric result, while an HPLC gymnemagenin grade at a far lower nominal percentage can carry a similar real saponin load. We quote 5%, 25%, 35%, 40% and 75% gymnemic acids by gravimetry and gymnemagenin-assayed HPLC grades, and we ask buyers to name the method and the reference standard on the purchase order so that incoming QC and the supplier COA are measuring the same thing. Water-soluble and ethanol-soluble variants, carrier-free and maltodextrin-carried, are produced to order. The material is wholly plant-derived: vegan and vegetarian, with no milk, egg, fish, crustacean, soy, peanut, tree nut or sesame input at any stage, and non-GMO. Gluten status follows the carrier, and the maltodextrin used in our carried grades is maize-derived, so a gluten-free declaration is issued on that basis; carrier-free grades are inherently gluten-free. Every consignment ships with a batch COA covering assay, loss on drying, ash, heavy metals to USP <232>, residual solvents to Class 3 limits, pesticide screening and microbiology, together with allergen, GMO, BSE/TSE-free and country-of-origin statements. Organic (NPOP/NOP/EU), Kosher and Halal certified lots are available on advance notice.