Saccharomyces boulardii
Saccharomyces cerevisiae var. boulardii · 6–20 billion CFU/g lyophilised
Live lyophilised Saccharomyces cerevisiae var. boulardii yeast powder, supplied at 6, 10 and 20 billion CFU/g for capsules, sachets and stick packs. Vegan, dairy-free, non-GMO. Bulk export from India.
Specifications
| Organism | Saccharomyces cerevisiae var. boulardii (Saccharomyces boulardii) — live, freeze-dried yeast |
| Reference strain | CNCM I-745, deposited at Institut Pasteur; the same organism is catalogued as CBS 5926. Generic non-deposited S. boulardii also supplied |
| Viable count | Standard grades 6, 10 and 20 billion CFU/g; 25 billion CFU/g on enquiry. Released with overage to hold the label claim to end of shelf life |
| Form and appearance | Free-flowing beige to light-brown lyophilised powder with a characteristic yeast odour |
| Moisture | Typically not more than 5.0%; freeze-dried cake water content is commonly held below 2% to protect viability |
| Water activity | Controlled low, typically ≤ 0.25. Indicative — confirm the contracted target on the lot specification |
| Dispersibility | Disperses in water to a suspension, not a true solution. Reconstitute in cool or lukewarm water only; heat destroys viable count |
| Microbiological purity | Salmonella, E. coli, S. aureus absent in the specified sample size; total coliforms and moulds within FSSAI limits for probiotic raw material |
| Heavy metals | Lead, arsenic, cadmium and mercury within FSSAI and Codex limits for food ingredients; reported per lot |
| Allergen status | Not derived from milk, egg, fish, crustacean, peanut or tree nut. Request the lot-specific soy and cereal-gluten declaration for the fermentation medium |
| Origin and dietary status | Microbial (yeast) origin — not bovine, porcine or marine. Vegan and vegetarian suitable, non-GMO. Note it is a yeast, so unsuitable for yeast-free claims |
| Regulatory | S. boulardii sits among the probiotic organisms recognised under FSSAI Schedule VII; verify the exact strain designation against the schedule in force |
| Storage and shelf life | 24 months at 2–8 °C in the original sealed foil laminate with desiccant, protected from light and humidity |
| HS code | 21021010 — active yeasts, culture yeast (see classification note) |
Saccharomyces boulardii is the only yeast in routine commercial probiotic use. Genomically it sits inside the species Saccharomyces cerevisiae and is correctly written Saccharomyces cerevisiae var. boulardii; the reference strain CNCM I-745, deposited at the Collection Nationale de Cultures de Micro-organismes at the Institut Pasteur, is the same organism catalogued as CBS 5926. Because it is a yeast rather than a bacterium, it is a fundamentally different raw material from the Bacillus and Lactobacillus cultures a formulator normally works with, and it is specified, handled and classified differently.
Thovek supplies the material as a freeze-dried (lyophilised) powder. Fermentation is followed by separation, cryoprotection and lyophilisation, which preserves cell viability better than heat-drying and gives a free-flowing beige powder of low residual moisture. Standard bulk grades run 6, 10 and 20 billion CFU/g, with 25 billion CFU/g available on enquiry; every lot is released against a plate count and shipped with a viability overage calculated to hold the declared count to the end of the stated shelf life. Buyers filling capsules, sachets or stick packs should tell us the target dose per unit and the fill equipment, since bulk density and flow are adjustable at the drying stage.
The organism is grown on a non-animal carbohydrate medium, so the powder is suitable for vegan and vegetarian positioning and is not derived from milk, egg, fish, crustacean, peanut or tree nut. Fermentation media and cryoprotectants vary between production campaigns, so the lot-specific soy and cereal-gluten declaration should always be requested rather than assumed. Live yeast is heat- and humidity-sensitive: ship and hold at 2–8 °C, keep the foil laminate sealed with its desiccant, and never reconstitute in hot water. Documentation supplied includes COA with viable count and method, allergen and GMO statements, heavy metals, microbiological purity, and a strain identity certificate where a named deposit is ordered.
Applications
probiotic capsules and sachetsstick-pack oral powderssingle-strain yeast supplementsmulti-strain probiotic blendsfunctional food premixestravel and lifestyle formatscompanion-animal supplements
Available grades
Bulk lyophilised powder at 6, 10 and 20 billion CFU/g; 25 billion CFU/g on enquiry. Available as generic S. boulardii or as the deposited CNCM I-745 (CBS 5926) strain with identity certificate. Capsule-fill and sachet-blend grades differ in bulk density and flow — specify the filling equipment. Non-GMO and vegan-certified lots available.
Packaging: 1 kg net in heat-sealed aluminium foil laminate pouches with desiccant, packed into HDPE drums or fibre drums of 5, 10 or 25 kg. Inner double polyethylene liner. Shipped with temperature-monitored cold chain at 2–8 °C; insulated shippers and data loggers available on request. Sample and pilot quantities from 100 g.
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