Probiotic + Prebiotic (Synbiotic)

Probiotic + Prebiotic (Synbiotic)

Strain-identified live cultures with a prebiotic substrate

A finished synbiotic in capsule or stick-sachet form: live, strain-identified cultures delivered with a prebiotic substrate such as chicory inulin, FOS or GOS, built to the buyer's own strain list and CFU.

Specifications

Product typeFinished-dosage synbiotic: live micro-organisms plus substrate(s) selectively utilised by host micro-organisms, per the ISAPP 2020 consensus definition
Design routeComplementary (independently evidenced probiotic plus prebiotic) or synergistic (substrate selected specifically for the co-delivered strain)
Probiotic fractionStrains from FSSAI Schedule VII: Lactobacillus and its successor genera, Bifidobacterium, Streptococcus thermophilus, Bacillus coagulans, Saccharomyces boulardii
Strain identificationDeclared to strain designation, not species alone; identity confirmed by 16S rRNA or whole-genome sequencing and stated on the CoA
PotencyMinimum 10^8 CFU in the recommended daily serving per FSSAI; label CFU held to end of shelf life by manufacturing overage
Prebiotic fractionChicory inulin, fructo-oligosaccharides, galacto-oligosaccharides or xylo-oligosaccharides; adult prebiotic intake capped at 40 g per 2000 kcal per day
Dosage formsSize 0 or 1 HPMC and gelatin capsules, delayed-release capsules for acid protection, 1-3 g stick sachets, or unfilled bulk blend
Appearance and dispersibilityFree-flowing off-white to cream powder blend; sachet grades disperse in cool water or juice without heating, which protects viability
Moisture controlBlend held at low water activity and packed with desiccant in a foil laminate; moisture ingress is the principal driver of CFU loss
Purity limitsHeavy metals, pesticide residues, Salmonella, E. coli, S. aureus, yeast and mould tested every lot against the buyer's agreed limits
Allergen statusFormulation-specific: dairy- or soy-based fermentation media can leave residual milk or soy protein. Dairy-free and soy-free media on request
Origin statusVegan with HPMC shells and dairy-free media; gelatin shells are bovine or porcine. No fish, crustacean, egg or nut input at any stage
Shelf life and storage18-24 months typical at 25 C or below in intact moisture-barrier packaging; 2-8 C storage extends viable count retention
HS code2106.90.99 (India ITC-HS 21069099) as a finished food supplement preparation; see classification note
A synbiotic is not simply a probiotic with fibre added. The 2020 ISAPP consensus (Swanson et al., Nature Reviews Gastroenterology & Hepatology) defines it as a mixture comprising live micro-organisms and substrate(s) selectively utilised by host micro-organisms. That definition splits the category in two: a complementary synbiotic pairs a probiotic and a prebiotic that each stand on their own evidence, while a synergistic synbiotic picks the substrate specifically for the strain travelling with it. Thovek builds both routes to the buyer's brief and supplies them as filled capsules, single-dose stick sachets or as a bulk blend for the buyer's own filling line. Strains are drawn from the list approved under Schedule VII of India's FSS (Health Supplements, Nutraceuticals, Food for Special Dietary Use...) Regulations, 2016 - Bifidobacterium, Streptococcus thermophilus, spore-forming Bacillus coagulans, the yeast Saccharomyces boulardii, and Lactobacillus together with the genera split out of it in the 2020 reclassification by Zheng et al., which broke the old genus into 25 genera including Lactiplantibacillus, Lacticaseibacillus, Limosilactobacillus, Levilactobacillus and Ligilactobacillus. Every organism is declared to its strain designation rather than species alone, because that is what the regulation and the buyer's label both require. FSSAI sets a floor of 10^8 CFU in the recommended daily serving and caps adult prebiotic intake at 40 g per 2000 kcal per day. Potency is set with a manufacturing overage so the printed CFU still holds at the end of the stated shelf life; low water activity, a desiccant and a foil-laminate moisture barrier carry the rest of that burden. Allergen and origin status is formulation-specific and has to be confirmed lot by lot, because it is decided by the fermentation medium rather than by the organism. Many lactic acid bacteria are propagated on dairy-derived media, which can leave residual milk protein unless a dairy-free medium is specified at order stage; soy peptone is the second common medium component. The capsule shell decides the vegan claim - HPMC for vegan and vegetarian, gelatin for bovine or porcine. No fish, crustacean, egg or nut material enters the process. Each lot ships with a CoA giving viable count by plate count, strain identity by sequencing, moisture and water activity, and a signed allergen and origin declaration.

Applications

Digestive health capsulesSingle-dose stick sachetsPrivate-label supplement linesFunctional beverage premixesSports nutrition stacksWomen's health formulationsSenior nutrition formatsCompanion animal supplements

Available grades

Complementary and synergistic formats; single-strain through 16-strain blends; vegetarian HPMC or bovine/porcine gelatin capsule shells; delayed-release capsules for acid protection; spore-forming Bacillus coagulans builds for ambient-stable and heat-processed applications; dairy-free and soy-free fermentation media; organic-compliant and non-GMO builds; label strengths from 1 to 100 billion CFU per dose.

Packaging: Bulk blend in 5, 10 or 25 kg aluminium-foil-laminate pouches or HDPE-lined fibre drums, double heat-sealed PE inner liner with desiccant sachets. Filled capsules supplied in 5,000 to 50,000 piece drums, or bottled, blistered or stick-packed to buyer artwork. Palletised and stretch-wrapped; shipped ambient with a temperature logger, or 2-8 C reefer where the strain mix warrants it. Pack size and MOQ negotiable against the strain specification.

Related products