Multi-Strain Probiotic Blend

Thovek supplies multi-strain probiotic blends built to a buyer's own strain list rather than sold as one fixed formula. A typical build combines species from the Lactobacillaceae family — Lactobacillus acidophilus, Lacticaseibacillus rhamnosus and Lacticaseibacillus casei, Lactiplantibacillus plantarum, Limosilactobacillus reuteri — with Bifidobacterium species such as B. longum, B. breve, B. bifidum and B. animalis subsp. lactis, and often Streptococcus thermophilus or the spore-forming Bacillus coagulans where a heat-tolerant, shelf-stable component is wanted. Genus names follow the 2020 Zheng et al. reclassification, which reorganised the family Lactobacillaceae and split the former genus Lactobacillus into Lactobacillus plus twenty-three newly described genera. Both the current and the former name are printed side by side on every document so a buyer's existing labels, specifications and regulatory dossiers reconcile without a rewrite. Each strain is fermented, harvested, cryoprotected and freeze-dried separately, then assayed and blended to a target viable count. Because live cultures lose potency slowly across shelf life, an overage is set at blending from the measured die-off rate of that specific blend, so the declared CFU is met at the end of the stated shelf life rather than only at release. Dryness is what protects that potency: the blend is finished to a low water activity, typically 0.25 or below, since survival of dried cells falls away once water activity rises much past that point, and it ships in foil laminate with desiccant. Fermentation medium drives the allergen declaration — dairy-peptone grades carry a milk declaration, soy or pea peptone grades carry a soy declaration, and a dairy-free, soy-free plant-peptone grade is available where a clean allergen statement is needed. The material is of microbial origin with no bovine, porcine, fish or crustacean input; the finished form is vegan when plant-peptone media and HPMC capsule shells are used, and gelatin shells are supplied only on written request with the animal origin declared. Every lot ships with a certificate giving strain-level identity against a public culture-collection accession, viable count by selective plate count (ISO 29981 for bifidobacteria and ISO 7889/IDF 117 principles for lactobacilli, with flow-cytometric active fluorescent units per ISO 19344 where a buyer prefers that method), water activity, pathogen screen and ICP-MS heavy metals. Strains are non-GMO and screened for acquired transferable antimicrobial-resistance genes, with MICs read against EFSA FEEDAP species cut-off values where the species carries EFSA QPS status. For the Indian market, FSSAI requires probiotic strains to be drawn from the Schedule VII list or otherwise approved by the Authority, to be declared to genus, species and strain, and to deliver not less than 10^8 CFU in the recommended serving size per day. Supply formats are bulk blended powder for the buyer's own encapsulation or sachet line, or finished HPMC capsules, sachets and stick-packs under contract manufacture. Thovek states composition and viable count only; any health or function claim, and the evidence behind it, remains the brand owner's responsibility in their own market.